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基于安全性和有效性合理且符合伦理地使用外用糖皮质激素。

Rational and ethical use of topical corticosteroids based on safety and efficacy.

作者信息

Rathi Sanjay K, D'Souza Paschal

机构信息

Consultant Dermatologist, Siliguri, West Bengal, India.

出版信息

Indian J Dermatol. 2012 Jul;57(4):251-9. doi: 10.4103/0019-5154.97655.

Abstract

Topical corticosteroids (TC) have greatly contributed to the dermatologist's ability to effectively treat several difficult dermatoses. The available range of formulations and potency gives flexibility to treat all groups of patients, different phases of disease, and different anatomic sites. However, the rapid rise in incidence of improper use of these drugs by dermatologists, general physicians, and patients threatens to bring disrepute to the entire group of these amazing drugs. Responsibility to disseminate proper knowledge regarding when, where, and how to use TC both to internists and patients rests primarily with the dermatologist. Benefits of rational and ethical use and the harm of overuse and misuse for nonmedical, specially for cosmetic purposes, should be clearly conveyed before penning a prescription involving TC. Simultaneous efforts to use political, legal, and other institutions to prevent misuse of these drugs by rationing their availability only through proper prescriptions will greatly help the cause. This will hopefully bring down both the extremes of ever increasing cases of steroid-induced dermatoses on one hand and the irrational fears of using TC in well justified indications on the other.

摘要

外用皮质类固醇(TC)极大地提升了皮肤科医生有效治疗多种难治性皮肤病的能力。现有的剂型和效力范围使治疗所有患者群体、疾病的不同阶段以及不同解剖部位具有灵活性。然而,皮肤科医生、普通内科医生和患者对这些药物使用不当的发生率迅速上升,这可能会给这类神奇药物的整个群体带来声誉损害。向内科医生和患者传播有关何时、何地以及如何使用TC的正确知识的责任主要在于皮肤科医生。在开具涉及TC的处方之前,应清楚地传达合理和合理使用的益处以及过度使用和滥用(特别是用于非医疗,尤其是美容目的)的危害。同时,通过仅通过适当处方来限制这些药物的供应,利用政治、法律和其他机构防止这些药物被滥用的努力将极大地有助于这项事业。这有望一方面减少类固醇诱导的皮肤病病例不断增加的极端情况,另一方面减少在合理适应症中使用TC的不合理恐惧。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9402/3401837/d688b2d19d52/IJD-57-251-g007.jpg

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