Maro E E, Lwakatare J
Department of Internal Medicine, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania.
East Afr Med J. 1997 Sep;74(9):539-42.
The clinical records of 702 patients starting antihypertensive treatment between 1985 and 1990 were collected and reviewed at the end of 1992. At the end of an average observation period of three years, 47% of the patients had dropped out of the cardiac clinic. The medication compliance of 146 patients was estimated by both interview method as well as by the pill count method in 1991 and 1992. Medication compliance was related to the frequency and time of dosing as well as to the number of drugs. Once daily regimens had better compliance than three times daily ones and medication compliance was greatest for morning dosing, second greatest for evening dosing and least for dosing at noon. A need for improvement of patient doctor communication was emphasised.
收集了1985年至1990年间开始接受抗高血压治疗的702例患者的临床记录，并于1992年底进行了回顾。在平均三年的观察期结束时，47%的患者已退出心脏科门诊。1991年和1992年通过访谈法和药丸计数法对146例患者的用药依从性进行了评估。用药依从性与给药频率、时间以及药物数量有关。每日一次给药方案的依从性优于每日三次给药方案，早晨给药的用药依从性最佳，其次是晚上给药，中午给药的依从性最差。强调了改善医患沟通的必要性。
