Abdulla M N, Sokrab T E, Zaidan Z A, Siddig H E, Ali M E
Department of Medicine, Faculty of Medicine, University of Khartoum, Sudan.
East Afr Med J. 1997 Sep;74(9):570-2.
In this study the clinical manifestation and the effect of corticosteroids on the course and the outcome of post malaria cerebellar ataxia on thirty adult Sudanese patients wr investigated. Twenty four patients with delayed ataxia, that is, ataxia occurring shortly after full recovery from otherwise uncomplicated, documented malaria and six patients who were found to be ataxic on recovery from cerebral malaria were included in the study. The distribution of the age, sex and various clinical aspects were outlined. Twelve randomly selected patients were given oral prednisolone. The corticosteroid was found to shorten the period of ataxia. It was also found that in patients who demonstrated cerebellar infarction or atrophy on computerised tomography the duration of ataxia was significantly long.
本研究调查了30例成年苏丹患者疟疾后小脑性共济失调的临床表现以及皮质类固醇对病程和结局的影响。24例为迟发性共济失调患者,即从无并发症的确诊疟疾完全康复后不久出现共济失调,6例为脑型疟疾康复后发现共济失调的患者纳入研究。概述了年龄、性别和各种临床特征的分布情况。随机选择12例患者口服泼尼松龙。发现皮质类固醇可缩短共济失调期。还发现,计算机断层扫描显示有小脑梗死或萎缩的患者,共济失调持续时间明显较长。