Au W Y
Science. 1976 Sep 10;193(4257):1015-7. doi: 10.1126/science.948759.
Addition of cortisol (10(-6) to 10(-8) M) and related glucocorticoid congeners to cultures of rat parathyroid glands stimulated dose-related increases in parathyroid hormone secretion; the addition of deoxycorticosterone or cortexolone was without effect. Cortexolone, however, inhibited the stimulatory activity of cortisol when both were added to the culture medium. This direct stimulatory effect of cortisol on parathyroid gland secretion may account in part for the increased concentration of parathyroid hormone in the serum of cortisol-treated animals.
向大鼠甲状旁腺培养物中添加皮质醇（10⁻⁶至10⁻⁸M）及相关糖皮质激素同系物可刺激甲状旁腺激素分泌呈剂量依赖性增加；添加脱氧皮质酮或皮质素则无此作用。然而，当皮质素和皮质醇同时添加到培养基中时，皮质素会抑制皮质醇的刺激活性。皮质醇对甲状旁腺分泌的这种直接刺激作用可能部分解释了经皮质醇处理的动物血清中甲状旁腺激素浓度升高的原因。
