O'Regan M E, Brown J K
Department of Paediatric Neurology, Royal Hospital for Sick Children, Edinburgh, UK.
Dev Med Child Neurol. 1998 Feb;40(2):82-9. doi: 10.1111/j.1469-8749.1998.tb15366.x.
Adrenocorticotrophin hormone (ACTH) has been used as an anticonvulsant for many years. In this paper, the use of ACTH in 23 children with intractable epilepsies is described. It was found that ACTH worked most effectively when the EEG showed benzodiazepine sensitivity. A mechanism of action of ACTH is proposed.
促肾上腺皮质激素（ACTH）作为一种抗惊厥药物已被使用多年。本文描述了促肾上腺皮质激素在23例难治性癫痫患儿中的应用情况。研究发现，当脑电图显示对苯二氮䓬敏感时，促肾上腺皮质激素的效果最为显著。文中还提出了促肾上腺皮质激素的作用机制。
