Sorokin B A, Popov A V, Sharapova G I, Antiukhov A V
City Clinic Hospital No 52, Moscow.
Klin Med (Mosk). 1997;75(10):49-51.
Combined therapy with plasmosorption has been performed in 22 patients aged 18-65 years suffering from different variants of psoriasis diagnosed 5 to 24 years before. Stable remission was achieved in 16 patients who exhibited normalization of peripheral blood characteristics including total protein and protein plasma fractions, lowering of CIC and middle molecular peptides concentration. The response was also obtained in severe psoriasis (psoriatic erythrodermia and arthropathic psoriasis). 11 patients remained in remission for at least 1 year. Due to plasmosorption the hospital stay of the patients reduced. Plasmosorption promoted detoxication, recovery of hepatic protein-synthetizing function, enhancement of plasma albumin detoxication ability.
对22名年龄在18至65岁之间、患有不同类型银屑病且在5至24年前被诊断出病情的患者进行了血浆吸附联合治疗。16名患者实现了稳定缓解，其外周血特征包括总蛋白和血浆蛋白组分恢复正常，循环免疫复合物（CIC）和中分子肽浓度降低。在重度银屑病（银屑病红皮病和关节病型银屑病）患者中也取得了疗效。11名患者缓解至少持续了1年。由于采用了血浆吸附疗法，患者的住院时间缩短。血浆吸附促进了解毒作用，恢复了肝脏蛋白质合成功能，增强了血浆白蛋白的解毒能力。
