Mlinarić J, Nincević N, Kostov D, Gnjatović D
Opća bolnica Zadar, Odjel za anesteziju.
Lijec Vjesn. 1997 Mar-Apr;119(3-4):113-6.
Oxygen saturation (SaO2) and end tidal CO2 determined by pulse oximetry and capnometry were monitored in 2440 surgical patients during elective head and neck, abdominal, traumatologic and orthopedic surgery. The incidence, severity and duration of hypoxemia and hypercarbia were studied as well as their causes. Equipment disconnections alarmed by capnometry were noted separately. Hypoxemia was defined as SaO2 < or = 90% and graded into three values of SaO2 and hypercarbia was defined as EtCO2 > or = 50 mmHg. Severe hypoxemia (SaO2 < or = 80%) occurred in 170 (8%) patients. A greater number of severe events occurred in children under 2 yr of age (p < 0.02). The pulse oximeter diagnosed hypoxemia before the signs and symptoms of hypoxemia were apparent (cyanosis or bradycardia). Severe hypoxemic episodes were unrelated to the duration of anesthesia. Equipment disconnections alarmed by capnometer were most frequent in head and neck surgery (p < 0.02). Capnometer alarmed disconnections before the signs of hypoxemia and hypercarbia occurred. No morbidity was documented in any patients who suffered an hypoxemia event. Pulse oximetry and capnometry enable early detection and removal of the majority of the ventilation mishaps before damage or even death occur.
在2440例接受择期头颈、腹部、创伤和骨科手术的外科患者中,通过脉搏血氧饱和度仪和二氧化碳监测仪监测氧饱和度(SaO2)和呼气末二氧化碳。研究了低氧血症和高碳酸血症的发生率、严重程度和持续时间及其原因。分别记录由二氧化碳监测仪发出警报的设备断开连接情况。低氧血症定义为SaO2≤90%,并根据SaO2的三个值进行分级,高碳酸血症定义为呼气末二氧化碳分压(EtCO2)≥50 mmHg。170例(8%)患者发生严重低氧血症(SaO2≤80%)。2岁以下儿童发生严重事件的数量更多(p<0.02)。在低氧血症的体征和症状(发绀或心动过缓)出现之前,脉搏血氧饱和度仪就能诊断出低氧血症。严重低氧血症发作与麻醉持续时间无关。由二氧化碳监测仪发出警报的设备断开连接情况在头颈手术中最为常见(p<0.02)。在低氧血症和高碳酸血症的体征出现之前,二氧化碳监测仪就发出了断开连接的警报。在发生低氧血症事件的任何患者中均未记录到发病情况。脉搏血氧饱和度仪和二氧化碳监测仪能够在损害甚至死亡发生之前早期发现并消除大多数通气事故。