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在制霉菌素处理的乳酸克鲁维酵母细胞中依赖外源三磷酸的核糖核酸合成

Ribonucleic acid synthesis dependent on exogenous triphosphates in nystatin-treated cells of of Kluyveromyces latis.

作者信息

Badaracco G, Cassani G

出版信息

Antimicrob Agents Chemother. 1976 May;9(5):748-53. doi: 10.1128/AAC.9.5.748.

DOI:10.1128/AAC.9.5.748
PMID:949173
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC429615/
Abstract

Kluyveromyces lactis cells treated with nystatin became permeable to ribonucleoside triphosphates. Although not viable, nystatin-treated cells were capable of sustaining ribonucleic acid synthesis. The system depended on the presence of divalent ions and the four nucleoside triphosphates, and was strongly stimulated by ammonium sulfate. The system utilized endogenous deoxyribonucleic acid as template. Synthesis of ribonucleic acid was associated with the cells and probably occurred internally.

摘要

用制霉菌素处理的乳酸克鲁维酵母细胞对三磷酸核糖核苷变得具有通透性。尽管经制霉菌素处理的细胞无法存活,但它们仍能够维持核糖核酸的合成。该系统依赖于二价离子和四种三磷酸核苷的存在,并受到硫酸铵的强烈刺激。该系统利用内源性脱氧核糖核酸作为模板。核糖核酸的合成与细胞相关联,可能发生在细胞内部。

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本文引用的文献

1
Rifampin: inhibition of ribonucleic acid synthesis after potentiation by amphotericin B in Saccharomyces cerevisiae.利福平:在酿酒酵母中经两性霉素B增强作用后对核糖核酸合成的抑制作用。
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Amphotericin B potentiation of rifampicin as an antifungal agent against the yeast phase of Histoplasma capsulatum.两性霉素B增强利福平作为抗荚膜组织胞浆菌酵母相的抗真菌剂的作用。
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Ribonucleic acid synthesis in bacteria treated with toluene.用甲苯处理的细菌中的核糖核酸合成
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Dependence of the sedimentation coefficient on molecular weight of RNA after reaction with formaldehyde.与甲醛反应后沉降系数对RNA分子量的依赖性。
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Transcription of ribonucleic acid in isolated mouse myeloma nuclei.分离的小鼠骨髓瘤细胞核中核糖核酸的转录
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Increased RNA synthesis in nuclear monolayers of WI-38 cells stimulated to proliferate.在被刺激增殖的WI-38细胞核单层中RNA合成增加。
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Rifamycins: a general view.利福霉素:概述
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