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雄激素缺乏所致女性性兴趣/唤起障碍:临床与心理测量问题

Female hypoactive sexual desire disorder due to androgen deficiency: clinical and psychometric issues.

作者信息

Warnock J K, Bundren J C, Morris D W

机构信息

Department of Psychiatry, University of Oklahoma Health Sciences Center-Tulsa 74129, USA.

出版信息

Psychopharmacol Bull. 1997;33(4):761-6.

PMID:9493489
Abstract

Menopause, surgical or naturally occurring, with reduced or deficient ovarian functioning has a major impact on morbidity and mortality in mid to late life. In particular, a growing body of literature is focusing on the role of androgens in maintaining women's health and emotional well-being. Further study is needed in the administration of physiologic levels of testosterone replacement therapy as an adjustment to estrogen replacement. The Sexual Energy Scale was developed to provide an objective means of measuring the change in a patient's subjective experience of vitality/sexual energy with androgen replacement therapy. The scale also provides a clinical indication for androgen replacement dosage adjustment. Advantages in using low doses of methyltestosterone in women with hypoactive sexual desire disorder are discussed.

摘要

绝经,无论是手术导致还是自然发生,伴随卵巢功能减退或不足,对中老年女性的发病率和死亡率都有重大影响。特别是,越来越多的文献聚焦于雄激素在维持女性健康和情绪幸福感方面的作用。在给予生理水平的睾酮替代疗法以作为雌激素替代疗法的一种调整方面,还需要进一步研究。性活力量表的开发是为了提供一种客观手段,用以测量患者在接受雄激素替代疗法时主观感受到的活力/性活力的变化。该量表还为雄激素替代剂量的调整提供了临床指征。文中讨论了在性欲减退障碍女性中使用低剂量甲基睾酮的优势。

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Female hypoactive sexual desire disorder due to androgen deficiency: clinical and psychometric issues.雄激素缺乏所致女性性兴趣/唤起障碍:临床与心理测量问题
Psychopharmacol Bull. 1997;33(4):761-6.
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Diabetes Care. 2011 Feb;34(2):332-4. doi: 10.2337/dc10-1714.
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Sexual dysfunction in the older woman: an overview of the current understanding and management.老年女性性功能障碍:当前认识与管理概述
Drugs Aging. 2004;21(10):655-75. doi: 10.2165/00002512-200421100-00004.
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Hormonal aspects of sexual dysfunction: the therapeutic use of exogenous androgens in men and women.
性功能障碍的激素方面:外源性雄激素在男性和女性中的治疗应用。
Curr Psychiatry Rep. 2000 Jun;2(3):215-22. doi: 10.1007/s11920-996-0011-5.
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Psychotropic drug-induced sexual function disorders: diagnosis, incidence and management.精神药物所致性功能障碍:诊断、发病率及管理
Drug Saf. 1998 Oct;19(4):299-312. doi: 10.2165/00002018-199819040-00005.