Hehemann K, Heising A
Leber Magen Darm. 1979 Dec;9(6):324-9.
A case report is given of a 73 years old woman suffering from Whipple's disease. Intermittant polyarthralgias, diarrhea, weight loss and laboratory signs of malabsorption had been present for 6 years, when diagnosis was established by biopsy: pathognomonic PAS-positive macrophages were demonstrated in the duodenal mucosa. A complete remission of the disease could be achieved after 100 mg of doxycycline had been administered continuously for a year. Some special details of the course of Whipple's disease in the higher age group are discussed.
报告了一例73岁患惠普尔病的女性病例。间歇性多关节痛、腹泻、体重减轻及吸收不良的实验室指标已持续6年,通过活检确诊:在十二指肠黏膜中发现了具有病理诊断意义的PAS阳性巨噬细胞。连续给予100毫克强力霉素一年后,疾病完全缓解。文中讨论了惠普尔病在老年患者中的一些特殊病程细节。