Delaunois L, Garrino M G
Cliniques de l'Université Catholique de Louvain Mont-Godinne, Yvoir, Belgique.
Rev Mal Respir. 1997 Dec;14 Suppl 5:S130-41.
Non-tuberculous mycobacteria (NTM) can be the etiologic agents of chronic pulmonary disease, lymphadenitis, skin and soft-tissue infection and disseminated disease in non-immunocompromised patients. The recognition of disease needs repeated isolation of the NTM from bronchopulmonary secretions or from tissue biopsies, and its identification by specific laboratory methods. A wide spectrum of clinical presentations and severity of disease can be found, from spontaneous healing to progressive and destructive lung disease, and death, according to predisposing conditions and mycobacterial species. The choice of surgical and drug treatment will depend on identification of specific pathogen and clinical evaluation.
非结核分枝杆菌(NTM)可成为非免疫功能低下患者慢性肺部疾病、淋巴结炎、皮肤及软组织感染和播散性疾病的病原体。疾病的诊断需要从支气管肺分泌物或组织活检中反复分离出NTM,并通过特定实验室方法进行鉴定。根据易感条件和分枝杆菌种类,可出现从自发愈合到进行性和破坏性肺部疾病乃至死亡等广泛的临床表现和疾病严重程度。手术和药物治疗的选择将取决于特定病原体的鉴定和临床评估。