Singer G, Hohl M K, Hering F, Anabitarte M
Division of Surgical Pathology, Cantonal Hospital, Baden, Switzerland.
Hum Pathol. 1998 Mar;29(3):299-301. doi: 10.1016/s0046-8177(98)90051-x.
A distinctive variant of a papillary noninvasive transitional cell carcinoma (TCC) of the vagina removed from a postmenopausal woman is described. The neoplasm was evaluated by immunohistochemistry. The designation of this neoplasm as a TCC is supported by its morphological features and its coexpression for cytokeratin (CK) 7 and CK 20. Its main feature is pagetoid infiltration into adjacent vaginal epithelium. This is the second reported case involving a transitional cell metaplasia (TCM) of the vagina, a possible precursor lesion of the TCC.
本文描述了一例从绝经后女性切除的阴道乳头状非浸润性移行细胞癌（TCC）的独特变体。通过免疫组织化学对该肿瘤进行了评估。该肿瘤形态学特征及其细胞角蛋白（CK）7和CK 20的共表达支持将其诊断为TCC。其主要特征是呈派杰样浸润至邻近的阴道上皮。这是第二例报道的涉及阴道移行细胞化生（TCM）的病例，TCM可能是TCC的前驱病变。
