Young L J, Wang Z, Insel T R
Dept of Psychiatry and Behavioral Sciences, Emory University School of Medicine, and the Yerkes Regional Primate Research Center, Atlanta, GA 30322, USA.
Trends Neurosci. 1998 Feb;21(2):71-5. doi: 10.1016/s0166-2236(97)01167-3.
A number of studies have implicated the neurohypophyseal peptides oxytocin and vasopressin in the central mediation of complex social behaviors, including affiliation, parental care and territorial aggression. Research on a monogamous rodent, the prairie vole (Microtus ochrogaster), suggests that these neuropeptides are also involved in the control of several behaviors associated with monogamy, including pair bonding, paternal care and mate guarding. Comparative studies using several species of vole have identified species-specific patterns of oxytocin- and vasopressin-receptor expression in the brain that appear to be associated with a monogamous versus non-monogamous social structure. Molecular studies suggest that changes in the regulation of oxytocin- and vasopressin-receptor gene expression underlie these species differences in receptor distribution and might provide a mechanism for the evolution of monogamy in voles.
多项研究表明，神经垂体肽催产素和加压素在复杂社会行为的中枢调节中发挥作用，这些行为包括亲密关系、亲代抚育和领地攻击。对一夫一妻制啮齿动物草原田鼠（Microtus ochrogaster）的研究表明，这些神经肽也参与控制与一夫一妻制相关的多种行为，包括配偶关系的形成、父性抚育和配偶守护。使用几种田鼠物种进行的比较研究已经确定了大脑中催产素和加压素受体表达的物种特异性模式，这些模式似乎与一夫一妻制和非一夫一妻制的社会结构有关。分子研究表明，催产素和加压素受体基因表达调控的变化是这些受体分布物种差异的基础，可能为田鼠一夫一妻制的进化提供一种机制。
