Sorgato A, Faggiano P, Aurigemma G P, Rusconi C, Gaasch W H
Divisione di Cardiologia, Ospedale S. Orsola-Fatebenefratelli, Brescia, Italy.
Chest. 1998 Feb;113(2):482-91. doi: 10.1378/chest.113.2.482.
With the longer life expectancy of the population, calcific aortic stenosis has become a common cardiac problem in the elderly. When patients with moderate to severe aortic stenosis become symptomatic, the prognosis is usually poor in absence of valve replacement and sudden death is a feared complication. It has been hypothesized that malignant ventricular arrhythmias could be responsible for the high incidence of sudden death in symptomatic patients with aortic stenosis. The purpose of this review is to analyze the prevalence, the electrophysiologic mechanisms, and the possible role of ventricular arrhythmias in the development of symptoms and in the outcome of adult subjects with aortic stenosis.
随着人口预期寿命的延长，钙化性主动脉瓣狭窄已成为老年人常见的心脏问题。当中重度主动脉瓣狭窄患者出现症状时，若不进行瓣膜置换，预后通常较差，猝死是令人担忧的并发症。有假说认为，恶性室性心律失常可能是有症状的主动脉瓣狭窄患者猝死发生率高的原因。本综述的目的是分析室性心律失常在成人主动脉瓣狭窄患者症状发生及预后中的患病率、电生理机制及可能作用。
