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一种鼠类艾滋病病毒的异性传播。

Heterosexual transmission of a murine AIDS virus.

作者信息

Okada Y, Abe E, Komuro K, Mizuochi T

机构信息

Department of Bacterial and Blood Products, National Institute of Infectious Diseases, Tokyo, Japan.

出版信息

J Virol. 1998 Mar;72(3):2541-3. doi: 10.1128/JVI.72.3.2541-2543.1998.

DOI:10.1128/JVI.72.3.2541-2543.1998
PMID:9499121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC109560/
Abstract

Heterosexual transmission of a murine leukemia virus mixture named LP-BM5 MuLV, which is known as the murine AIDS virus, was investigated. Our results indicated that the heterosexual transmission of LP-BM5 MuLV occurs in both directions with high frequency and that the frequencies of virus transmission in the cervix and penis are higher than those in other genital organs. The results suggested that infection by LP-BM5 MuLV via heterosexual transmission may initially take place at particular retrovirus-sensitive sites (cells) in the genital organs.

摘要

对一种名为LP - BM5 MuLV的鼠白血病病毒混合物(即所谓的鼠艾滋病病毒)的异性传播进行了研究。我们的结果表明,LP - BM5 MuLV的异性传播在两个方向上都高频发生,并且在子宫颈和阴茎中的病毒传播频率高于其他生殖器官。结果提示,通过异性传播感染LP - BM5 MuLV可能最初发生在生殖器官中特定的逆转录病毒敏感部位(细胞)。

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本文引用的文献

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The association between circumcision status and human immunodeficiency virus infection among homosexual men.男同性恋者的包皮环切状态与人类免疫缺陷病毒感染之间的关联。
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Female to male transmission of human immunodeficiency virus type 1: risk factors for seroconversion in men.人类免疫缺陷病毒1型的女性向男性传播:男性血清转化的危险因素
Lancet. 1989 Aug 19;2(8660):403-7. doi: 10.1016/s0140-6736(89)90589-8.
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Defective virus is associated with induction of murine retrovirus-induced immunodeficiency syndrome.缺陷病毒与鼠逆转录病毒诱导的免疫缺陷综合征的诱导有关。
Proc Natl Acad Sci U S A. 1989 May;86(10):3862-6. doi: 10.1073/pnas.86.10.3862.
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Detection of HIV-related protein in testes and prostates of patients with AIDS.
Am J Clin Pathol. 1990 Feb;93(2):196-201. doi: 10.1093/ajcp/93.2.196.
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White blood cells and HIV-1 in semen from vasectomised seropositive men.输精管结扎血清阳性男性精液中的白细胞与HIV-1
Lancet. 1991 Aug 31;338(8766):573-4. doi: 10.1016/0140-6736(91)91139-l.