[糖尿病母亲的婴儿（IDM）。II——纤连蛋白与围产期发病率]
[Infants of diabetic mothers (IDM). II -- Fibronectin and perinatal morbidity].
作者信息
Martín Carballo G, Codoceo Alquila R, Fernández Cano G, Hawkins Carranza F, Grande Aragón C, Velasco Hernando A, Gracia Bouthelier R
机构信息
Servicio de Endocrinología, Hospital Infantil La Paz, Madrid.
出版信息
An Esp Pediatr. 1997 Sep;47(3):302-10.
OBJECTIVE
The objective of this study was to determine fibronectin levels in umbilical cord blood of infants of diabetic mothers (IDM) and evaluate a possible correlation with perinatal pathology.
PATIENTS AND METHODS
A prospective study of 58 IDM (33 males and 25 females) and 58 control newborns (NB) (33 males and 25 females) was carried out.
RESULTS
There were no differences in fibronectin levels between the two groups nor between the sexes. Perinatal morbidity was higher in the IDM group, but there was no correlation between fibronectin levels and the presence of perinatal pathology.
CONCLUSIONS
Fibronectin levels are not useful in the perinatal evaluation of infants of diabetic mothers.
目的
本研究的目的是测定糖尿病母亲婴儿（IDM）脐带血中的纤连蛋白水平，并评估其与围产期病理学之间的可能相关性。
患者与方法
对58例IDM（男33例，女25例）和58例对照新生儿（NB）（男33例，女25例）进行了一项前瞻性研究。
结果
两组之间以及不同性别之间的纤连蛋白水平均无差异。IDM组的围产期发病率较高，但纤连蛋白水平与围产期病理学的存在之间无相关性。
结论
纤连蛋白水平在糖尿病母亲婴儿的围产期评估中并无用处。
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