Wilsdorf G, Graf G
Institut für Pharmakologie und Toxikologie, Fachbereiches Veterinärmedizin, Freien Universität Berlin.
Berl Munch Tierarztl Wochenschr. 1998 Jan;111(1):21-6.
The main aspects of the development of veterinary toxicology from the time of foundation of the veterinary college in Berlin 1790 up to 1945 are being described. The first toxicological experiments were made in 1821. The teaching of veterinary toxicology in Berlin began in 1872 and the foundation of the Department of Pharmacology as a part of Small Animal Clinic was in 1886. The historical development may be divided in four periods. In the first, from 1821-1830, acute and chronical intoxications were examined. The second period, from 1831-1870, has been determined by experimental drug toxicology and the beginning of environmental toxicology. In 1935 were the foundation of an independent Department of Pharmacology and Toxicology and in this time the toxicological research reached an internationally important level.
本文描述了从1790年柏林兽医学院成立到1945年期间兽医毒理学发展的主要方面。首次毒理学实验于1821年进行。柏林兽医学院于1872年开始教授兽医毒理学，1886年药理学系作为小动物诊所的一部分成立。历史发展可分为四个时期。第一个时期是1821年至1830年，主要研究急性和慢性中毒。第二个时期是1831年至1870年，以实验药物毒理学和环境毒理学的开端为特征。1935年成立了独立的药理学和毒理学系，此时毒理学研究达到了国际重要水平。
