Paccalin M, Roblot P, Goujon J M, Ramassamy A, Debiais F, Delaire L, Vidal E, Becq-Giraudon B
Service de médecine interne, centre hospitalier universitaire La Milétrie, Poitiers.
Rev Med Interne. 1997;18(12):939-44. doi: 10.1016/s0248-8663(97)80113-0.
Seventy-two cases of primary Sjögren's syndrome, according to the European classification criteria, were studied looking for a correlation between anatomic criteria and clinico-biological signs in this disease. Labial salivary gland biopsy was performed in all patients and anatomic criteria were evaluated according to both Chisholm and Chomette scales. Work-up included recording of functional and clinical signs. Our study shows no clinico-histological correlation in Sjögren's syndrome. Moreover, we did not find any correlation between the two histological scales. We think, therefore, that labial salivary gland biopsy appears to be an important step in Sjögren's syndrome diagnosis according to European criteria. However, it does not present any benefit in patient treatment.
根据欧洲分类标准，对72例原发性干燥综合征患者进行了研究，以寻找该疾病解剖学标准与临床生物学体征之间的相关性。对所有患者进行了唇腺活检，并根据Chisholm和Chomette量表评估了解剖学标准。检查包括记录功能和临床体征。我们的研究表明，干燥综合征不存在临床组织学相关性。此外，我们未发现两种组织学量表之间存在任何相关性。因此，我们认为，根据欧洲标准，唇腺活检似乎是干燥综合征诊断的重要步骤。然而，它对患者治疗并无任何益处。
