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[Reversal of the pressor effect of PGF2alpha in the rat (author's transl)].

作者信息

Damas J

出版信息

Experientia. 1976 Jun 15;32(6):725-7. doi: 10.1007/BF01919855.

DOI:10.1007/BF01919855
PMID:950019
Abstract

In normal rats, prostaglandin F2alpha is a potent vasoconstrictor. The corresponding systemic hypertension is progressively attenuated by tachyphylaxis, revealing a longlasting fall of blood pressure. Tachyphylaxis is accelerated by previous injection of arachidonic acid and bradyskinin. The vasodepressive activity of PGF2alpha is inhibited by indomethacin.

摘要

相似文献

1
[Reversal of the pressor effect of PGF2alpha in the rat (author's transl)].
Experientia. 1976 Jun 15;32(6):725-7. doi: 10.1007/BF01919855.
2
Effects of prostaglandins E2, I2 and F2 alpha, arachidonic acid and indomethacin on pressor responses to norepinephrine in conscious rats.前列腺素E2、I2和F2α、花生四烯酸及吲哚美辛对清醒大鼠去甲肾上腺素升压反应的影响
Prostaglandins. 1980 Jun;19(6):855-64. doi: 10.1016/0090-6980(80)90119-7.
3
The effects of arachidonic acid, indomethacin and SC-19220 on guinea-pig tracheal muscle tone.花生四烯酸、吲哚美辛和SC - 19220对豚鼠气管肌张力的影响。
Eur J Pharmacol. 1975 Feb;30(2):148-53. doi: 10.1016/0014-2999(75)90093-x.
4
Prostaglandin F2alpha reduces the algesic effect of bradykinin by antagonizing the pain enhancing action of endogenously released prostaglandin E.前列腺素F2α通过拮抗内源性释放的前列腺素E的疼痛增强作用来降低缓激肽的致痛效应。
Br J Pharmacol. 1977 Mar;59(3):385-91. doi: 10.1111/j.1476-5381.1977.tb08390.x.
5
Potentiation of bradykinin-induced vascular permeability increase by prostaglandin E2 and arachidonic acid in rabbit skin.前列腺素E2和花生四烯酸对缓激肽诱导的兔皮肤血管通透性增加的增强作用。
Prostaglandins. 1975 Nov;10(5):747-58. doi: 10.1016/0090-6980(75)90003-9.
6
Relationship between central actions of bradykinin and prostaglandins in the conscious rat.清醒大鼠中缓激肽的中枢作用与前列腺素之间的关系。
Neuropharmacology. 1982 Mar;21(3):267-72. doi: 10.1016/0028-3908(82)90197-6.
7
Dose-response effects of prostaglandin F2alpha on the rabbit oviduct: reproductive endocrine influence and tachyphylaxis.前列腺素F2α对兔输卵管的剂量反应效应：生殖内分泌影响及快速耐受性。
Prostaglandins. 1976 Jul;12(1):127-37. doi: 10.1016/s0090-6980(76)80011-1.
8
Antagonism of the pulmonary vasoconstrictor response to prostaglandin F2alpha by N-dimethylamino substitution of prostaglandin F2alpha.通过对前列腺素F2α进行N - 二甲基氨基取代来拮抗其对肺血管收缩反应的作用。
J Pharmacol Exp Ther. 1978 Jul;206(1):139-42.
9
Comparative effects of arachidonic acid, bisenoic prostaglandins, and an endoperoxide analog on the canine pulmonary vascular bed.
Can J Physiol Pharmacol. 1977 Dec;55(6):1369-77. doi: 10.1139/y77-182.
10
Bradykinin and prostaglandin E1, E2 and F2alpha-induced macromolecular leakage in the hamster cheek pouch.缓激肽以及前列腺素E1、E2和F2α诱导的仓鼠颊囊大分子渗漏
Prostaglandins Med. 1978 Nov;1(5):397-410. doi: 10.1016/0161-4630(78)90126-x.

本文引用的文献

1
Microcirculatory effects of prostaglandins.
Can J Physiol Pharmacol. 1969 Jul;47(7):627-34. doi: 10.1139/y69-109.
2
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.抑制前列腺素合成作为阿司匹林类药物的作用机制。
Nat New Biol. 1971 Jun 23;231(25):232-5. doi: 10.1038/newbio231232a0.
3
[Action of arachidonic acid on the arterial pressure of the rabbit before and after heparin].[花生四烯酸对肝素化前后家兔动脉血压的作用]
Arch Int Pharmacodyn Ther. 1974 Apr;208(2):363-4.
4
Evidence for the presence of a prostaglandin E 2 -9-keto reductase in rat organs.大鼠器官中存在前列腺素E 2 -9-酮还原酶的证据。
Biochem Biophys Res Commun. 1973 Jun 8;52(3):717-24. doi: 10.1016/0006-291x(73)90996-0.
5
Proceedings: The reduction of prostaglandin E2 to prostaglandin F2alpha by various animal tissues.论文集：各种动物组织将前列腺素E2还原为前列腺素F2α的过程。
Br J Pharmacol. 1974 Sep;52(1):109P-110P.
6
Cardiovascular responses to prostaglandin F2 alpha in spontaneously hypertensive rats.自发性高血压大鼠对前列腺素F2α的心血管反应
Prostaglandins. 1974 Aug 25;7(4):345-53. doi: 10.1016/s0090-6980(74)80090-0.
7
Studies on the mechanism of the hypertensive effect of prostaglandin F2-alpha.前列腺素F2-α升压作用机制的研究。
J Pharmacol Exp Ther. 1968 Mar;160(1):1-10.
8
[Prostaglandin liberation by bradykinin in the rat].[缓激肽在大鼠体内释放前列腺素]
C R Seances Soc Biol Fil. 1974;168(2-3):375-8.
9
[Proceedings: Influence of tryptophan on the hypotensive effect of arachidonic acid].[会议论文：色氨酸对花生四烯酸降压作用的影响]
Arch Int Physiol Biochim. 1974 Oct;82(4):742-4.
10
Correlation between inhibition by anti-inflammatory substances, of arachidonic acid-induced hypotension and of prostaglandin biosynthesis in vitro.
Biochem Pharmacol. 1976 Apr 15;25(8):983-5. doi: 10.1016/0006-2952(76)90328-2.