Ryska A, Jirousek Z
Department of Pathology, Charles University Medical Faculty Hospital, Hradec Králové, Czech Republic.
Cesk Patol. 1997 Nov;33(4):118-22.
Giant cell epulis (peripheral giant cell granuloma) is a tumorlike condition of the gingiva found predominantly in elderly women. A case of peripheral giant cell granuloma of the mandibular gingiva, examined by fine needle aspiration biopsy, is herein reported. A 51-year-old woman presented with a three week history of bleeding from a six cm tumor located in the central part of the mandible. On radiography, an osteolytic lesion was present, suspicious of malignancy. An aspiration biopsy revealed microscopic features suggesting the diagnosis of a giant cell lesion of possibly malignant nature. Surgical resection was performed. Histological examination showed giant cell epulis destroying the mandibular bone. Differential diagnosis of this lesion is widely discussed.
巨细胞龈瘤（周围性巨细胞肉芽肿）是一种主要见于老年女性牙龈的肿瘤样病变。本文报告一例通过细针穿刺活检检查的下颌牙龈周围性巨细胞肉芽肿病例。一名51岁女性，下颌骨中部有一个6厘米的肿瘤，出血三周。影像学检查显示有溶骨性病变，怀疑为恶性。穿刺活检显示显微镜下特征提示可能为恶性性质的巨细胞病变。进行了手术切除。组织学检查显示巨细胞龈瘤破坏了下颌骨。对该病变的鉴别诊断进行了广泛讨论。
