Kaw Y T
Cytopathology Laboratory, Wishard Memorial Hospital, Indianapolis, Indiana.
Acta Cytol. 1994 May-Jun;38(3):475-8.
Two patients with recurrent central giant cell granuloma (CGCG) who underwent fine needle aspiration biopsy are reported. This lesion has a distinct clinicoradiologic profile and occurs almost exclusively in the mandible and/or maxilla of young individuals. The essential cytologic findings included a dual cell population consisting of mononuclear stromal cells and multinucleate giant cells. These features were considered not specific for the diagnosis of CGCG and are identical to those of osteitis fibrosa cystica and giant cell tumor of bone. If the features are taken together with the clinical, radiologic and laboratory data, the diagnosis of CGCG is possible. The utility of osseous fine needle aspiration biopsy and the clinical, radiologic and cytologic findings of bone lesions containing giant cells are discussed.
报告了两名接受细针穿刺活检的复发性中央巨细胞肉芽肿（CGCG）患者。该病变具有独特的临床放射学特征，几乎仅发生于年轻人的下颌骨和/或上颌骨。基本的细胞学发现包括由单核基质细胞和多核巨细胞组成的双细胞群。这些特征被认为对CGCG的诊断不具有特异性，与骨纤维性骨炎囊肿和骨巨细胞瘤的特征相同。如果将这些特征与临床、放射学和实验室数据相结合，则有可能诊断CGCG。讨论了骨细针穿刺活检的实用性以及含有巨细胞的骨病变的临床、放射学和细胞学发现。
