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老年人缺血性心脏病——病因及发病机制

[Ischemic heart disease in the elderly--etiologic factors and pathogenesis].

作者信息

Janocha J

机构信息

Oddziału Kardiologii Szpitala Rejonowego w Radomsku.

出版信息

Przegl Lek. 1997;54(11):806-11.

PMID:9501694
Abstract

Presented analysis of risk factors of coronary heart disease in the elderly indicate that two of them that is hypertension and diabetes are considered the most important in this age group. No significant predictive value of smoking, obesity, family history or hypercholesterolaemia was found. Increased incidence of coronary heart disease in the elderly can be related to cumulation of above risk factors throughout their life. In the second part of the study the pathogenesis of coronary heart disease is discussed with the conclusion that in myocardial infarction the mechanism leading to occlusion of coronary artery may depend on patients age. The fluent progress of senile, physiological process in degenerative, pathological ones allows in this age group of patients only for quantitative differentiation of these conditions and arbitrary established criteria of norm and pathology.

摘要

对老年人冠心病危险因素的分析表明,其中两个因素,即高血压和糖尿病,被认为是该年龄组中最重要的因素。未发现吸烟、肥胖、家族病史或高胆固醇血症有显著的预测价值。老年人冠心病发病率的增加可能与这些危险因素在其一生中的累积有关。在研究的第二部分,讨论了冠心病的发病机制,得出的结论是,在心肌梗死中,导致冠状动脉闭塞的机制可能取决于患者的年龄。在这个年龄组的患者中,从衰老的生理过程到退化的病理过程的平稳进展,使得只能对这些情况进行定量区分,并任意确定正常和病理的标准。

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