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比较POSSUM和朴茨茅斯预测方程在预测血管手术后死亡情况方面的表现。

Comparison of POSSUM and the Portsmouth predictor equation for predicting death following vascular surgery.

作者信息

Wijesinghe L D, Mahmood T, Scott D J, Berridge D C, Kent P J, Kester R C

机构信息

Department of Vascular and Endovascular Surgery, St James's University Hospital, Leeds, UK.

出版信息

Br J Surg. 1998 Feb;85(2):209-12. doi: 10.1046/j.1365-2168.1998.00709.x.

DOI:10.1046/j.1365-2168.1998.00709.x
PMID:9501818
Abstract

BACKGROUND

The Physiological and Operative Severity Score for enUmeration of Mortality and morbidity (POSSUM) scoring system has been proposed as an accurate predictor of death which takes account of case mix. It appears to overpredict death, and may have drawbacks which prevent accurate individual or subgroup analysis. An alternative system, the Portsmouth predictor equation for mortality (P-POSSUM) may have overcome these problems, but its apparent advantage could be related to inappropriate analysis of POSSUM predictions.

METHODS

Some 312 patients having arterial procedures were studied. POSSUM and P-POSSUM scores were used to predict death and compared with actual outcomes. The observed:predicted (O:E) mortality ratios were calculated by two methods for each of the scoring systems. First the analysis devised by the inventors of POSSUM was used and second the method devised for P-POSSUM.

RESULTS

The O:E ratio for POSSUM using its recommended 'exponential' method of analysis was 1.14, but it was 0.59 if the P-POSSUM 'linear' analysis was used. The O:E ratio for P-POSSUM using its correct method of analysis was 0.89, but it was 0.67 if the method of analysis devised for POSSUM was used.

CONCLUSION

The O:E ratios for POSSUM and P-POSSUM were close to unity when the appropriate analysis was performed. Both POSSUM and P-POSSUM overpredicted death if the incorrect analysis was used.

摘要

背景

用于计算死亡率和发病率的生理与手术严重程度评分系统(POSSUM)已被提出作为一种考虑病例组合的准确死亡预测指标。它似乎高估了死亡率,并且可能存在一些缺点,妨碍了准确的个体或亚组分析。另一种系统,朴茨茅斯死亡率预测方程(P-POSSUM)可能已经克服了这些问题,但其明显优势可能与对POSSUM预测的不当分析有关。

方法

对约312例行动脉手术的患者进行了研究。使用POSSUM和P-POSSUM评分来预测死亡,并与实际结果进行比较。对于每个评分系统,通过两种方法计算观察到的与预测的(O:E)死亡率比值。首先使用POSSUM发明者设计的分析方法,其次使用为P-POSSUM设计的方法。

结果

使用POSSUM推荐的“指数”分析方法时,POSSUM的O:E比值为1.14,但使用P-POSSUM的“线性”分析时,该比值为0.59。使用P-POSSUM正确的分析方法时,P-POSSUM的O:E比值为0.89,但使用为POSSUM设计的分析方法时,该比值为0.67。

结论

进行适当分析时,POSSUM和P-POSSUM的O:E比值接近1。如果使用不正确的分析方法,POSSUM和P-POSSUM都会高估死亡率。

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