Himel H N, Ratliff C R, Baruch L D, Rodeheaver G T
Department of Plastic Surgery, University of Virginia Medical Center, Charlottesville 22908, USA.
J Burn Care Rehabil. 1998 Jan-Feb;19(1 Pt 1):62-5. doi: 10.1097/00004630-199801000-00014.
The clinical benefits of using the VENTEX Wound Dressing System (VWDS) (The Kendall Co.) in the management of donor site wounds were evaluated in this pilot study involving 10 informed and consenting patients. The study was a prospective, randomized, controlled study in which one donor site wound was managed with VWDS, and the other donor site wound on the same patient was managed by our standard of care, which involved the use of Xeroform gauze (The Kendall Co.). Each donor site wound was independently assessed daily for pain, rate of reepithelialization, adverse reactions, and ease of dressing use while patients were hospitalized. Quality of scar was assessed during regularly scheduled follow-up visits. The use of VWDS eliminated donor site pain and accelerated reepithelialization compared with Xeroform gauze. There were no adverse reactions associated with the use of VWDS. In contrast, there were two cases of suspected infection at the donor sites treated with Xeroform gauze. The VWDS was more complicated to apply and use compared with Xeroform gauze. There were no differences observed in scar quality of donor sites treated with these dressings.
在这项涉及10名知情并同意参与的患者的初步研究中,评估了使用VENTEX伤口敷料系统(VWDS,肯德尔公司)处理供皮区伤口的临床益处。该研究是一项前瞻性、随机对照研究,其中一个供皮区伤口采用VWDS处理,同一患者的另一个供皮区伤口采用我们的标准护理方法处理,即使用Xeroform纱布(肯德尔公司)。在患者住院期间,每天对每个供皮区伤口的疼痛、再上皮化速率、不良反应以及敷料使用的便利性进行独立评估。在定期随访时评估瘢痕质量。与Xeroform纱布相比,使用VWDS可消除供皮区疼痛并加速再上皮化。使用VWDS未出现不良反应。相比之下,使用Xeroform纱布处理的供皮区有2例疑似感染病例。与Xeroform纱布相比,VWDS的应用和使用更为复杂。使用这些敷料处理的供皮区瘢痕质量未观察到差异。