Moghal N E, Milford D V, Darbyshire P
Department of Nephrology, The Birmingham Children's Hospital, Ladywood, UK.
Pediatr Nephrol. 1998 Jan;12(1):14-5. doi: 10.1007/s004670050393.
We report the use of granulocyte colony-stimulating factor (G-CSF) in a renal transplant recipient in whom neutropenia developed following a presumed viral infection. G-CSF was successful in producing a rise in neutrophil count which coincided with a resolution of fever; there was no adverse effect on renal function. This is the first use of G-CSF in a paediatric renal transplant recipient, and its use should be considered for the immunosuppressed child with persistent neutropenia.
我们报告了1例肾移植受者在发生疑似病毒感染后出现中性粒细胞减少症，使用粒细胞集落刺激因子（G-CSF）进行治疗的情况。G-CSF成功使中性粒细胞计数升高，同时发热消退；对肾功能无不良影响。这是G-CSF首次用于小儿肾移植受者，对于持续中性粒细胞减少的免疫抑制患儿，应考虑使用G-CSF。
