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粒细胞集落刺激因子对辐射诱导的中性粒细胞减少症的逆转作用。

Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor.

作者信息

Marks L B, Friedman H S, Kurtzberg J, Oakes W J, Hockenberger B M

机构信息

Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710.

出版信息

Med Pediatr Oncol. 1992;20(3):240-2. doi: 10.1002/mpo.2950200312.

Abstract

Myelosuppression is a common sequelae of radiotherapy, occasionally delaying the completion of treatment. In this report, we describe successful reversal of radiation-induced neutropenia in a child receiving craniospinal irradiation by granulocyte colony-stimulating factor (G-CSF). We suggest that G-CSF be considered as supportive care in patients in whom neutropenia develops during radiotherapy.

摘要

骨髓抑制是放疗常见的后遗症,偶尔会延误治疗的完成。在本报告中,我们描述了一名接受全脑全脊髓照射的儿童,通过粒细胞集落刺激因子(G-CSF)成功逆转了放疗引起的中性粒细胞减少。我们建议,对于放疗期间出现中性粒细胞减少的患者,应考虑将G-CSF作为支持性治疗措施。

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