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粒细胞集落刺激因子对辐射诱导的中性粒细胞减少症的逆转作用。

Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor.

作者信息

Marks L B, Friedman H S, Kurtzberg J, Oakes W J, Hockenberger B M

机构信息

Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710.

出版信息

Med Pediatr Oncol. 1992;20(3):240-2. doi: 10.1002/mpo.2950200312.

DOI:10.1002/mpo.2950200312
PMID:1374149
Abstract

Myelosuppression is a common sequelae of radiotherapy, occasionally delaying the completion of treatment. In this report, we describe successful reversal of radiation-induced neutropenia in a child receiving craniospinal irradiation by granulocyte colony-stimulating factor (G-CSF). We suggest that G-CSF be considered as supportive care in patients in whom neutropenia develops during radiotherapy.

摘要

骨髓抑制是放疗常见的后遗症,偶尔会延误治疗的完成。在本报告中,我们描述了一名接受全脑全脊髓照射的儿童,通过粒细胞集落刺激因子(G-CSF)成功逆转了放疗引起的中性粒细胞减少。我们建议,对于放疗期间出现中性粒细胞减少的患者,应考虑将G-CSF作为支持性治疗措施。

相似文献

1
Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor.粒细胞集落刺激因子对辐射诱导的中性粒细胞减少症的逆转作用。
Med Pediatr Oncol. 1992;20(3):240-2. doi: 10.1002/mpo.2950200312.
2
Use of recombinant granulocyte-colony stimulating factor to treat neutropenia occurring during craniospinal irradiation.使用重组粒细胞集落刺激因子治疗颅脑脊髓照射期间发生的中性粒细胞减少症。
Int J Radiat Oncol Biol Phys. 1993 Aug 1;26(5):845-50. doi: 10.1016/0360-3016(93)90500-u.
3
Effect of prophylactic granulocyte-colony stimulating factor (G-CSF) on acute hematological toxicity in medulloblastoma patients during craniospinal irradiation (CSI).预防性粒细胞集落刺激因子(G-CSF)对行颅脊照射(CSI)的髓母细胞瘤患者急性血液学毒性的影响。
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4
Value of granulocyte colony stimulating factor in radiotherapy induced neutropenia: clinical and laboratory studies.
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Treatment of neutropenia in a renal transplant recipient with granulocyte colony-stimulating factor.用粒细胞集落刺激因子治疗肾移植受者的中性粒细胞减少症。
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G-CSF treatment of leucopenia during fractionated radiotherapy.分次放疗期间粒细胞集落刺激因子治疗白细胞减少症
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The use of G-CSF during craniospinal irradiation.在全脑全脊髓照射期间使用粒细胞集落刺激因子。
Int J Radiat Oncol Biol Phys. 1993 Aug 1;26(5):905-6; discussion 907. doi: 10.1016/0360-3016(93)90509-t.
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Reversal of gold-induced neutropenia with granulocyte colony-stimulating factor (G-CSF).粒细胞集落刺激因子(G-CSF)逆转金诱导的中性粒细胞减少症。
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Neonatal sepsis with neutropenia: granulocyte-colony stimulating factor (G-CSF).新生儿败血症伴中性粒细胞减少:粒细胞集落刺激因子(G-CSF)
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Effects of a formulary change from granulocyte colony-stimulating factor to granulocyte-macrophage colony-stimulating factor on outcomes in patients treated with myelosuppressive chemotherapy.从粒细胞集落刺激因子改为粒细胞-巨噬细胞集落刺激因子的处方变更对接受骨髓抑制性化疗患者结局的影响。
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引用本文的文献

1
Impact of acute hematological toxicity on treatment interruptions during cranio-spinal irradiation in medulloblastoma: a tertiary care institute experience.急性血液学毒性对髓母细胞瘤全脑全脊髓放疗中断的影响:一家三级医疗机构的经验。
J Neurooncol. 2017 Sep;134(2):309-315. doi: 10.1007/s11060-017-2524-7. Epub 2017 Jun 2.
2
Granulocyte colony-stimulating factor in the treatment of acute radiation syndrome: a concise review.粒细胞集落刺激因子在急性放射综合征治疗中的应用:简要综述
Molecules. 2014 Apr 16;19(4):4770-8. doi: 10.3390/molecules19044770.
3
Omeprazole-induced blood dyscrasia in a clozapine-treated patient.
奥美拉唑致氯氮平治疗患者血液系统异常
Innov Clin Neurosci. 2012 Sep;9(9):14-7.
4
[Use of G-CSF (Neupogen) in multimodal treatment in radiotherapy].[粒细胞集落刺激因子(惠尔血)在放疗多模式治疗中的应用]
Strahlenther Onkol. 1998 Nov;174(11):551-5. doi: 10.1007/BF03038291.
5
[Comparison of 2 strategies in the treatment of radiogenic leukopenia using granulocyte colony stimulating factor].[使用粒细胞集落刺激因子治疗放射性白细胞减少症的两种策略比较]
Strahlenther Onkol. 1997 Mar;173(3):170-1. doi: 10.1007/BF03039276.
6
[G-CSF in radiochemotherapy].
Strahlenther Onkol. 1997 Feb;173(2):76-82. doi: 10.1007/BF03038926.
7
Filgrastim. A review of its pharmacological properties and therapeutic efficacy in neutropenia.非格司亭。其药理学特性及对中性粒细胞减少症治疗效果的综述。
Drugs. 1994 Nov;48(5):731-60. doi: 10.2165/00003495-199448050-00007.