Jain L, Ferre C, Vidyasagar D
Department of Pediatrics, University of Illinois, Chicago, USA.
J Matern Fetal Med. 1998 Jan-Feb;7(1):23-7. doi: 10.1002/(SICI)1520-6661(199801/02)7:1<23::AID-MFM6>3.0.CO;2-T.
Racial differences in the outcome of pregnancies complicated by hypertension (HTN) were examined using data obtained from a large perinatal data base with 109,428 consecutive deliveries from 1982 to 1987. Black women had a higher prevalence of hypertension than white women (prevalence ratio 2.3, 95% CI 2.2, 2.5). However, when compared to normotensive women of similar race, white hypertensive women showed a higher risk for adverse pregnancy outcome than black hypertensives as indicated by the higher odds ratio for prematurity (OR: 1.7 for white [W], 1.2 for black [B]), low birth weight (OR: 2.4 W; 1.5 B), intrauterine growth retardation (OR: 4.4 W; 1.6 B) and perinatal death (OR 2.3 W; 1.2 B). Hypertension was associated with a 156 g reduction in birthweight of newborns in whites as compared to a 63 g reduction in blacks. Further studies are needed to understand the racial differences in the impact of HTN on pregnancy outcome.
利用1982年至1987年期间109428例连续分娩的大型围产期数据库中的数据,研究了患有高血压(HTN)的妊娠结局中的种族差异。黑人女性高血压患病率高于白人女性(患病率比为2.3,95%置信区间为2.2至2.5)。然而,与同种族血压正常的女性相比,白人高血压女性出现不良妊娠结局的风险高于黑人高血压女性,早产(白人[W]的比值比为1.7,黑人[B]为1.2)、低出生体重(白人比值比为2.4;黑人比值比为1.5)、宫内生长受限(白人比值比为4.4;黑人比值比为1.6)和围产期死亡(白人比值比为2.3;黑人比值比为1.2)的比值比更高表明了这一点。与黑人新生儿出生体重减少63克相比,高血压使白人新生儿出生体重减少156克。需要进一步研究以了解高血压对妊娠结局影响的种族差异。