Little H L, Chan C C
Mod Probl Ophthalmol. 1979;20:121-6.
48 patients with central retinal vein occlusion by clinical diagnosis and 10 eyes by histopathological documentation were studied and reviewed. Only 1 eye developed retinal neovascularization. Rubeosis iridis occurs in 14% of clinical cases and all of histopathologic cases. 10 long-standing neovascular glaucoma enucleated eyes following central retinal vein occlusion show absence of retinal endothelial cells. The absence of retinal capillary endothelial cells seems to be significant in explaining the rare occurrence of retinal neovascularization following central retinal vein occlusion. However, the small number sampling may reflect a biased result. Further prospective studies with more cases and time observation are required to draw the final conclusion.
对48例临床诊断为视网膜中央静脉阻塞的患者以及10只经组织病理学证实的眼睛进行了研究和回顾。仅1只眼睛发生了视网膜新生血管形成。虹膜红变在14%的临床病例以及所有组织病理学病例中出现。10只因视网膜中央静脉阻塞后发生新生血管性青光眼而摘除的长期患病眼睛显示视网膜内皮细胞缺失。视网膜毛细血管内皮细胞的缺失似乎对于解释视网膜中央静脉阻塞后视网膜新生血管形成的罕见发生具有重要意义。然而，少量样本可能反映出有偏差的结果。需要进一步进行更多病例和长期观察的前瞻性研究才能得出最终结论。
