CGP 9000: a new orally active, broad-spectrum cephalosporin.
作者信息
Zak O, Vischer W A, Schenk C, Tosch W, Zimmermann W, Regös J, Suter E R, Kradolfer F, Gelzer J
出版信息
J Antibiot (Tokyo). 1976 Jun;29(6):653-5. doi: 10.7164/antibiotics.29.653.
PMID:950320
Abstract
CGP 9000, (7-[D-2-amino-2-(1,4-cyclohexadienyl)-acetamido]-3-methoxy-3-cephem-4-carboxylic acid), is a new broad-spectrum cephalosporin antibiotic. Its antibacterial activity in vitro (MIC) is similar, but its bactericidal efficacy superior to that of cephalexin and cephradine. Upon oral administration to mice infected with various bacteria, CGP 9000 is, in general, 2 to 7 times more effective than either cephalexin or cephradine.
摘要
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