Murray M J, del Piero F, Jeffrey S C, Davis M S, Furr M O, Dubovi E J, Mayo J A
Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute, Leesburg, USA.
J Vet Intern Med. 1998 Jan-Feb;12(1):36-41. doi: 10.1111/j.1939-1676.1998.tb00494.x.
Of 17 foals born on a Thoroughbred breeding farm between March and April 1995, infection with equine herpesvirus type 1 (EHV-1) was associated with neonatal morbidity in 5 foals, 3 of which died or were euthanized. Morbidity and mortality were associated with pulmonary inflammation, and EHV-1 was identified in the lungs of the 3 foals that died. All neonatal EHV-1 infections occurred in foals of mares housed in the same pasture and barn. No other clinical manifestations of EHV-1 infection (e.g., abortion, neurologic disease, or respiratory disease) occurred during this outbreak. Three foals were treated with acyclovir (1 died, 2 survived), which may have influenced the clinical outcome in the surviving foals.
1995年3月至4月间，在一个纯种马繁殖场出生的17匹幼驹中，1型马疱疹病毒（EHV-1）感染与5匹幼驹的新生儿发病有关，其中3匹死亡或被安乐死。发病率和死亡率与肺部炎症有关，并且在死亡的3匹幼驹的肺部发现了EHV-1。所有新生儿EHV-1感染均发生在同一牧场和马厩中饲养的母马所生的幼驹身上。在此次疫情期间，未出现EHV-1感染的其他临床表现（如流产、神经疾病或呼吸道疾病）。3匹幼驹接受了阿昔洛韦治疗（1匹死亡，2匹存活），这可能影响了存活幼驹的临床结局。
