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星形细胞瘤的化疗:概述

Chemotherapy of astrocytomas: an overview.

作者信息

Armstrong T S, Gilbert M R

机构信息

Department of Neurology, Emory University, Atlanta, GA 30222, USA.

出版信息

Semin Oncol Nurs. 1998 Feb;14(1):18-25. doi: 10.1016/s0749-2081(98)80039-9.

DOI:10.1016/s0749-2081(98)80039-9
PMID:9503511
Abstract

OBJECTIVES

To provide an overview of the use of chemotherapy in the treatment of malignant brain tumors, with an emphasis on malignant gliomas.

DATA SOURCES

Published articles, research studies, and reference books.

CONCLUSIONS

Chemotherapy has primarily been used in a adjuvant setting after radiation therapy for primary brain tumors. This focus has not had a significant effect on survival. In an effort to more effectively treat the tumor, innovative chemotherapy treatments have been developed. These include the use of neoadjuvant chemotherapy, changes in timing of administration, new classes of chemotherapeutic agents, new routes of delivery, and augmentation of the body's own immune system to treat the tumor.

IMPLICATIONS FOR NURSING PRACTICE

It is the challenge of the oncology nurse caring for the patient with a malignant brain tumor to gain knowledge of the disease process, side effect management, and the most up-to-date treatment regimens.

摘要

目的

概述化疗在恶性脑肿瘤治疗中的应用,重点是恶性胶质瘤。

数据来源

已发表的文章、研究报告和参考书籍。

结论

化疗主要用于原发性脑肿瘤放疗后的辅助治疗。这种治疗重点对生存率没有显著影响。为了更有效地治疗肿瘤,已开发出创新的化疗方法。这些方法包括使用新辅助化疗、改变给药时间、新型化疗药物、新的给药途径以及增强机体自身免疫系统来治疗肿瘤。

对护理实践的启示

肿瘤护理人员在照顾恶性脑肿瘤患者时面临的挑战是了解疾病过程、副作用管理以及最新的治疗方案。

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