Salamanca F
Unidad de Investigación Médica en Genética Humana, Hospital de Pediatría, Centro Médico Nacional, Siglo XXI IMSS, México, D.F.
Gac Med Mex. 1997;133 Suppl 1:71-4.
In recent years, methodology has been implemented with the purpose to establish DNA diagnostic banking by means of transformed cell lines, direct extracted DNA, cryopreserved blood or other tissues and the study of samples embedded in paraffin. The objectives of the storage of individual DNA samples are for academic and research purposes, principally for gene mapping, and for diagnostic services to those who are at genetic risk and may be interested in family-based linkage testing, for establishing forensic DNA data bank, and for tissue transplantation. These developments implicate important legal and ethical issues, and institute rights and obligations of the donors and of the persons that conduct the banks.
近年来，已实施了一些方法，目的是通过转化细胞系、直接提取的DNA、冷冻保存的血液或其他组织以及对石蜡包埋样本的研究来建立DNA诊断库。储存个体DNA样本的目的是用于学术和研究，主要用于基因图谱绘制，为有遗传风险且可能对基于家族的连锁检测感兴趣的人提供诊断服务，建立法医DNA数据库，以及用于组织移植。这些进展涉及重要的法律和伦理问题，并确立了捐赠者以及经营这些库的人员的权利和义务。
