Boothroyd J C, Hehl A, Knoll L J, Manger I D
Int J Parasitol. 1998 Jan;28(1):3-9. doi: 10.1016/s0020-7519(97)00182-3.
As for any intracellular parasite, the surface of the Apicomplexan parasite Toxoplasma gondii must fulfil many functions including a role in attachment, signalling, invasion, transport and interaction with the immune response of the host. In this review, we describe the current state of knowledge on the molecules that are found on the surface of the different developmental stages of this parasite and speculate as to how at least some of these multiple functions are fulfilled. Special emphasis is given to the growing family of surface antigens that are related to the tachyzoite-specific surface antigen 1. We conclude that the surface (of tachyzoites, at least) is both more and less complex than previously thought: there are more proteins present but their sequences suggest that the majority may share a similar overall structure typified by surface antigen 1.
对于任何细胞内寄生虫而言，顶复门寄生虫刚地弓形虫的表面必须履行多种功能，包括在附着、信号传导、入侵、运输以及与宿主免疫反应相互作用中发挥作用。在本综述中，我们描述了关于该寄生虫不同发育阶段表面所发现分子的当前知识状态，并推测这些多种功能中至少有一些是如何实现的。特别强调了与速殖子特异性表面抗原1相关的不断增长的表面抗原家族。我们得出结论，（至少速殖子的）表面比以前认为的既更复杂又更简单：存在更多的蛋白质，但其序列表明大多数可能共享以表面抗原1为代表的相似总体结构。
