Singh L N, Higano S, Takahashi S, Abe Y, Sakamoto M, Kurihara N, Furuta S, Tamura H, Yanagawa I, Fujii T, Ishibashi T, Maruoka S, Yamada S
Department of Radiology, Tohoku University School of Medicine, Sendai, Japan.
AJNR Am J Neuroradiol. 1998 Feb;19(2):275-80.
We used functional MR imaging to evaluate cortical activation in the precentral, central, and postcentral regions of the contralateral and ipsilateral cerebral hemispheres during left- and right-handed motor tasks.
Ten healthy right-handed volunteers were studied with echo-planner MR imaging (1.5 T) while performing alternating finger apposition tasks with both hands. During the hand tasks, the areas of activated pixels were compared between subregions (precentral, central, and postcentral) of the contralateral and ipsilateral sensorimotor cortex.
The activated area of the contralateral sensorimotor cortex was significantly larger than that of the ipsilateral cortex during tasks with either hand, whereas the ipsilateral activated area was significantly larger during the left-handed task than during the right-handed task. Ipsilateral activation was greatest in the precentral region, less in the central region, and least prominent in the postcentral region.
Our results confirmed those of previous investigators that ipsilateral activation is more pronounced during left-sided movements than during right-sided movements. The variation in activation of the precentral, central, and postcentral subregions suggests different roles of the ipsilateral and contralateral hemispheres during motor tasks.
我们运用功能磁共振成像技术，评估在左手和右手运动任务期间，对侧和同侧大脑半球中央前回、中央回及中央后回区域的皮质激活情况。
对10名健康右利手志愿者进行回波平面磁共振成像（1.5T）研究，他们双手同时进行交替手指对指任务。在手部任务期间，对比对侧和同侧感觉运动皮层各亚区域（中央前回、中央回和中央后回）激活像素的面积。
在任何一只手执行任务时，对侧感觉运动皮层的激活面积均显著大于同侧皮层，而在左手任务期间同侧激活面积显著大于右手任务期间。同侧激活在中央前回区域最大，在中央回区域较小，在中央后回区域最不明显。
我们的结果证实了先前研究者的发现，即同侧激活在左侧运动期间比右侧运动期间更明显。中央前回、中央回和中央后回亚区域激活的差异表明，在运动任务期间同侧和对侧半球发挥着不同作用。
