Menconi G F, Melfi F M, Mussi A, Palla A, Ambrogi M C, Angeletti C A
Department of Surgery, Service of Thoracic Surgery, Pisa, Italy.
Eur J Cardiothorac Surg. 1998 Jan;13(1):66-70. doi: 10.1016/s1010-7940(97)00294-7.
In selected patients with giant bullous emphysema GBE and in those with specific complications, surgery may be the treatment of choice.
In the period January 1993-February 1996 we performed 34 VATS treatments in 29 patients affected by GBE. There were 22 (76%) males and 7 (24%) females, with a mean age of 54 years (range 24 74). In 23 cases, a pneumothorax (PNX) was present at admission, while 6 patients were treated by choice. Altogether. we performed 23 resections of sessile bullae (type 2 of Reid) by using a linear endoscopic stapling device (Endo-path 35 and 45 mm) and 11 ligatures of pedicled bullae (type 1 of Reid) by loop (Endo-loop 'PDS'). The mean number of charges for every treatment was 8 (range 4-21). The largest bullae were perforated and deprived of incarcerated air. They were then twisted on the axis perpendicular to the base in order to improve the manoeuvrability of the lesion and favour the correct placement of the Endo-path or Endo-loop. GBE was bilateral in 7 cases: one of these was treated bilaterally in the same surgical stage, other 4 were treated by staged operations.
We experienced two conversions to open thoracotomy (one sessile giant bulla inside the fissura; 1 case of strong tuberculous pleural adhesions). Two patients, underwent a second operation by open thoracotomy because of a prolonged air leak. We have two peri-operative deaths, both to respiratory failure. Altogether, in 23 out of 29 (79%) cases VATS was effective and the mean hospital stay was 6 days (range 3-16). At a mean follow up of 16 months (range 1-36) no recurrence of PNX was observed.
VATS may be considered as a suitable surgical technique to approach GBE and, in most cases, it is effective.
对于部分巨大泡性肺气肿(GBE)患者及有特定并发症的患者,手术可能是首选治疗方法。
在1993年1月至1996年2月期间,我们对29例GBE患者进行了34次电视辅助胸腔镜手术(VATS)治疗。其中男性22例(76%),女性7例(24%),平均年龄54岁(范围24 - 74岁)。23例患者入院时存在气胸(PNX),6例为择期治疗。我们总共使用线性内镜缝合装置(Endo-path 35和45 mm)对23例无蒂大疱(Reid Ⅱ型)进行了切除,并使用圈套器(Endo-loop 'PDS')对11例有蒂大疱(Reid Ⅰ型)进行了结扎。每次治疗的平均费用为8次(范围4 - 21次)。最大的大疱被穿刺并排出其中的积气。然后将其在垂直于底部的轴线上扭转,以提高病变的可操作性,并便于正确放置Endo-path或Endo-loop。7例GBE患者为双侧病变:其中1例在同一手术阶段进行了双侧治疗,另外4例采用分期手术治疗。
我们有2例转为开胸手术(1例为裂内无蒂巨大大疱;1例为严重结核性胸膜粘连)。2例患者因漏气时间延长接受了开胸二次手术。我们有2例围手术期死亡,均死于呼吸衰竭。总共,29例中的23例(79%)VATS治疗有效,平均住院时间为6天(范围3 - 16天)。平均随访16个月(范围1 - 36个月),未观察到PNX复发。
VATS可被视为治疗GBE的一种合适手术技术,且在大多数情况下是有效的。