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提取低分子量肽后哺乳动物DNA模板容量的扩增

Amplification of template capacity of mammalian DNA following extraction of low molecular weight peptides.

作者信息

Gianfranceschi G L, Amici D, Guglielmi L

出版信息

Physiol Chem Phys. 1979;11(6):507-15.

PMID:95050
Abstract

Experiments were carried out to evaluate the physical and functional modifications of DNA from several mammalian tissues following alkaline extraction (pH 9.5). The results indicate that such extraction provokes removal of firmly bound low molecular weight non-histone peptides involved in a general mechanism regulating the template capacity of DNA.

摘要

开展了实验以评估碱性提取（pH 9.5）后几种哺乳动物组织中DNA的物理和功能变化。结果表明，这种提取会促使去除与调节DNA模板能力的一般机制相关的紧密结合的低分子量非组蛋白肽。

相似文献

1
Amplification of template capacity of mammalian DNA following extraction of low molecular weight peptides.提取低分子量肽后哺乳动物DNA模板容量的扩增
Physiol Chem Phys. 1979;11(6):507-15.
2
Low molecular weight peptide from calf's liver mitochondrial DNA: structure and effect on DNA as a template.源自小牛肝脏线粒体DNA的低分子量肽：结构及其作为模板对DNA的影响
Physiol Chem Phys Med NMR. 1995;27(4):281-91.
3
Template strand gap bypass is a general property of prokaryotic RNA polymerases: implications for elongation mechanisms.模板链缺口绕过是原核生物RNA聚合酶的一个普遍特性：对延伸机制的影响。
Biochemistry. 1996 Nov 26;35(47):14999-5008. doi: 10.1021/bi961455x.
4
Effect of internal protein of T2 bacteriophage on template activity of DNA in the RNA polymerase system.T2噬菌体内部蛋白质对RNA聚合酶系统中DNA模板活性的影响。
Mol Biol. 1974 Jan;7(4):439-45.
5
Small peptides bound to polysomal RNA inhibit gene expression in cell-free systems, replication of stimulated lymphocytes and DNA repair in isolated chromatin.与多聚核糖体RNA结合的小肽可抑制无细胞系统中的基因表达、刺激淋巴细胞的复制以及分离染色质中的DNA修复。
Physiol Chem Phys Med NMR. 1985;17(3):307-23.
6
[Localization of binding sites of E. coli DNA-dependent RNA-polymerase with photosensitive template analogs].
Bioorg Khim. 1986 Aug;12(8):1023-9.
7
Small acidic peptides from wheat germ chromatin. I. Isolation and biochemical characterization.
Physiol Chem Phys Med NMR. 1992;24(2):97-107.
8
[Transcription of DNA by RNA polymerases of E. coli and calf thymus].[大肠杆菌和小牛胸腺的RNA聚合酶对DNA的转录]
Mol Biol (Mosk). 1975 Jan-Feb;9(1):70-7.
9
Isolation and characterization of small phosphorylated peptides controlling transcription "in vitro" from trout testis chromatin DNA.
Physiol Chem Phys Med NMR. 1988;20(2):91-108.
10
[Isolation and properties of an insulin-like peptide from a high molecular a-component of commercial bovine insulin].[从市售牛胰岛素的高分子α组分中分离胰岛素样肽及其性质]
Acta Biol Med Ger. 1974;33(4):399-406.

引用本文的文献

1
A pool of peptides extracted from wheat bud chromatin inhibits tumor cell growth by causing defective DNA synthesis.从麦芽染色质中提取的一组肤抑制肿瘤细胞生长，因为它引起了有缺陷的 DNA 合成。
Cell Div. 2013 Aug 6;8:11. doi: 10.1186/1747-1028-8-11. eCollection 2013.
2
A class of DNA-binding peptides from wheat bud causes growth inhibition, G2 cell cycle arrest and apoptosis induction in HeLa cells.一类来自麦芽的DNA结合肽可导致HeLa细胞生长抑制、G2期细胞周期阻滞及凋亡诱导。
Mol Cancer. 2009 Jul 31;8:55. doi: 10.1186/1476-4598-8-55.
3
DNA-binding peptides from rat liver and Novikoff hepatoma cells: quantitative level and possible biochemical differences.
Mol Biol Rep. 1983 Aug;9(3):169-74. doi: 10.1007/BF00775363.
4
Isolation and characterization of DNA-binding peptides from the serum: inhibition of transcription and comparison with the tissue peptides.
Mol Biol Rep. 1982 Nov 30;8(4):217-23. doi: 10.1007/BF00776583.
5
Control of RNA and protein synthesis in phytohemagglutinin-stimulated human lymphocytes by chromatin peptides from calf thymus.
Mol Biol Rep. 1980 Dec 31;6(4):225-8. doi: 10.1007/BF00777529.
6
Small acidic peptides are bound to E. coli DNA.
Mol Biol Rep. 1991 Feb;15(1):9-18. doi: 10.1007/BF00369895.