Tetsuguchi M, Nomura S, Katayama M, Sugawa-Katayama Y
Department of Food and Nutrition, Faculty of Human Life Science, Osaka City University, Japan.
J Nutr Sci Vitaminol (Tokyo). 1997 Oct;43(5):515-27. doi: 10.3177/jnsv.43.515.
The effects of curdlan and gellan gum on the gastrointestinal function were studied, and the morphological structure of the intestinal mucosal surface was observed by scanning electron microscopy of rats fed curdlan and gellan gum diets for four weeks. The rats fed the curdlan diet showed a significant increase in the weight of the cecum and its contents and a decrease in fecal weight as compared to the rats fed a cellulose diet. On the other hand, the rats fed the gellan gum diet showed a weight loss in cecal contents and weight gain in colonic contents. The transit time of the gastrointestinal tract was extended by curdlan supplementation whereas it was shortened by gellan gum supplementation. The surface structures of the ileal and cecal mucosa were markedly abnormal in the rats fed the curdlan diet: the microvilli were tightly packed and had fallen out at places. In the gellan gum-fed rats, the tops of the ileal and cecal microvilli adhered to one another and were covered with their contents. There was no difference in the surface structure of colonic mucosa among the cellulose, curdlan and gellan gum diet groups.
研究了可得然胶和结冷胶对胃肠功能的影响,并通过扫描电子显微镜观察了连续四周喂食可得然胶和结冷胶日粮的大鼠肠道黏膜表面的形态结构。与喂食纤维素日粮的大鼠相比,喂食可得然胶日粮的大鼠盲肠及其内容物重量显著增加,粪便重量减少。另一方面,喂食结冷胶日粮的大鼠盲肠内容物重量减轻,结肠内容物重量增加。补充可得然胶会延长胃肠道的转运时间,而补充结冷胶则会缩短转运时间。喂食可得然胶日粮的大鼠回肠和盲肠黏膜的表面结构明显异常:微绒毛紧密排列,部分地方有脱落。在喂食结冷胶的大鼠中,回肠和盲肠微绒毛顶部相互粘连,并被其内容物覆盖。纤维素、可得然胶和结冷胶日粮组之间结肠黏膜的表面结构没有差异。