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在喂食含有问荆(Equisetum arvense L.)的胆固醇饮食的大鼠中发生皮炎。

Occurrence of dermatitis in rats fed a cholesterol diet containing field horsetail (Equisetum arvense L.).

作者信息

Maeda H, Miyamoto K, Sano T

机构信息

Faculty of Health and Living Sciences, Naruto University of Education, Japan.

出版信息

J Nutr Sci Vitaminol (Tokyo). 1997 Oct;43(5):553-63. doi: 10.3177/jnsv.43.553.

DOI:10.3177/jnsv.43.553
PMID:9505240
Abstract

The effects of dietary field horsetail (Equisetum arvense L.) powder on lipid components were studied in rats fed a 20% casein diet with or without cholesterol (0.5% cholesterol and 0.15% sodium cholate) for 14 days. The ingestion of 0.4% or 4% Equisetum arvense L. powder did not influence food intake or growth. However, a cholesterol diet with Equisetum arvense L. at 4% caused dermatitis at the neck, head and back in about 20-65% of the rats. This dermatitis was reversed when the diet was changed to commercial pellets. There were no apparent effects on serum or liver lipids in the rats fed Equisetum arvense L. irrespective of dietary cholesterol. Serum IgE levels measured by enzyme-linked immunoassay revealed that the induction of IgE may not necessarily be involved in the dermatitis caused by the intake of Equisetum arvense L. These results suggest that the ingestion of large amounts of Equisetum arvense L. as cooking material is not recommended for those with a cholesterol-rich diet.

摘要

在以含20%酪蛋白的饲料喂养、添加或不添加胆固醇(0.5%胆固醇和0.15%胆酸钠)的大鼠中研究了膳食木贼粉对脂质成分的影响,喂养14天。摄入0.4%或4%的木贼粉不影响食物摄入量或生长。然而,含4%木贼的胆固醇饮食在约20 - 65%的大鼠中导致颈部、头部和背部出现皮炎。当饮食改为商业颗粒饲料时,这种皮炎得到缓解。无论膳食胆固醇如何,喂食木贼的大鼠的血清或肝脏脂质均无明显影响。通过酶联免疫测定法测量的血清IgE水平表明,IgE的诱导不一定与摄入木贼引起的皮炎有关。这些结果表明,不建议胆固醇丰富饮食的人群将大量木贼作为烹饪材料食用。

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引用本文的文献

1
Evaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats.膳食给予问荆对F344大鼠的亚慢性毒性评价。
J Toxicol Pathol. 2010 Dec;23(4):245-51. doi: 10.1293/tox.23.245. Epub 2010 Dec 16.