Hayward R D
J Neurol Neurosurg Psychiatry. 1976 Jun;39(6):526-30. doi: 10.1136/jnnp.39.6.526.
Twenty-seven cases diagnosed as having malignant melanoma affecting the central nervous system have been studied. In 20 patients the tumours represented secondary spread from elsewhere, but there were six who had a primary melanoma either of the spinal cord, leptomeninges, or brain. Confusion exists in the literature about how to differentiate primary from secondary tumours but this suggests several clinical factors which may indicate that the lesion is probably a primary one. This method of categorizing the cases is supported by the differences in duration of symptoms and survival times for each group and a simple classification can therefore be proposed.
对27例被诊断为患有影响中枢神经系统的恶性黑色素瘤的病例进行了研究。在20例患者中，肿瘤代表来自其他部位的继发性扩散，但有6例患者患有脊髓、软脑膜或脑部的原发性黑色素瘤。关于如何区分原发性肿瘤和继发性肿瘤，文献中存在混淆，但这表明了几个可能表明病变可能是原发性病变的临床因素。每组症状持续时间和生存时间的差异支持了这种病例分类方法，因此可以提出一种简单的分类方法。
