Heule F, Tahapary G J, Bello C R, van Joost T
Department of Dermato-Venereology, Academic Hospital Rotterdam-Dijkzigt, The Netherlands.
Contact Dermatitis. 1998 Feb;38(2):78-82. doi: 10.1111/j.1600-0536.1998.tb05657.x.
The possibility for patch testing procedures to detect contact allergy was examined in 85 hospitalized patients with forms of psoriasis. Exclusion criteria were active lesions on the back, the use of strong topical corticosteroids, methotrexate, cyclosporin and UV therapy. After screening, a group of 47 patients with different forms of psoriasis were selected for patch testing. Personal history, including topical treatment, occupation and domestic circumstances, were reasons to extend the standard series of allergens. Tars, nickel sulfate, perfume and balsam of Peru scored high. The overall positive rate was 68%. This is higher than that observed in earlier studies. The unexpected results are discussed in the light of the possible mechanism of action.
在85例住院的银屑病患者中，研究了斑贴试验检测接触性过敏的可能性。排除标准为背部有活动性皮损、使用强效外用皮质类固醇、甲氨蝶呤、环孢素及紫外线治疗。筛选后，选择47例不同类型银屑病患者进行斑贴试验。个人史，包括局部治疗、职业和家庭环境，是扩展标准变应原系列的原因。焦油、硫酸镍、香水和秘鲁香脂的阳性率较高。总阳性率为68%。这高于早期研究中观察到的阳性率。根据可能的作用机制对意外结果进行了讨论。
