Vujkovac B, Lavre J, Sabovic M
Department of Nephrology and Dialysis, Slovenj Gradec General Hospital, Slovenia.
Am J Kidney Dis. 1998 Mar;31(3):536-8. doi: 10.1053/ajkd.1998.v31.pm9506694.
Colonic angiodysplasias are a common source of gastrointestinal bleeding in patients with end-stage renal disease (ESRD). It is well known that bleeding from angiodysplasias can be a difficult therapeutic problem. This report describes a hemodialysis patient who suffered acute (massive) and chronic gastrointestinal bleeding from colonic angiodysplasias. Because endoscopic ablation could not be performed and resection of the colon was refused, pharmacological treatment with the antifibrinolytic agent tranexamic acid was attempted. A successful management of both the acute and chronic bleeding was achieved. No complications in terms of arterial or venous thrombosis were observed.
结肠血管发育异常是终末期肾病（ESRD）患者胃肠道出血的常见原因。众所周知，血管发育异常引起的出血可能是一个棘手的治疗难题。本报告描述了一名血液透析患者，因结肠血管发育异常而发生急性（大量）和慢性胃肠道出血。由于无法进行内镜下消融且患者拒绝结肠切除术，遂尝试使用抗纤维蛋白溶解剂氨甲环酸进行药物治疗。急性和慢性出血均得到成功处理。未观察到动脉或静脉血栓形成方面的并发症。
