Newman V, Rock C L, Faerber S, Flatt S W, Wright F A, Pierce J P
Department of Family and Preventive Medicine, University of California-San Diego, La Jolla 92093-0901, USA.
J Am Diet Assoc. 1998 Mar;98(3):285-92. doi: 10.1016/s0002-8223(98)00068-6.
To develop a method of collecting, organizing, and analyzing information on nutrient and nonnutrient dietary supplement use by women at risk for breast cancer recurrence as a component of nutrition assessment and monitoring, and to describe the characteristics associated with dietary supplement use in this population at enrollment in a clinical trial to prevent breast cancer recurrence.
Cross-sectional descriptive study design.
Women diagnosed with breast cancer within the previous 4 years (n=435).
Dietary supplements reported in four 24-hour dietary recalls were categorized according to primary nutrient and nonnutrient contents. Prevalence of dietary supplement use is described. Associations between supplement use and demographic and participant characteristics were examined using chi(2) analysis and logistic regression.
Dietary supplement use was reported by 80.9% of the women. Increased likelihood of supplement use was associated with demographic (eg, older age, higher level of education, white race vs other ethnic groups) and personal (eg, lower body mass index, moderate alcohol consumption) characteristics. Use of vitamin C and related compounds, other nutrients (eg, n-3 fatty acids, evening primrose oil), and herbal products was inversely associated with months since diagnosis; use of miscellaneous supplements (eg, shark cartilage) was directly associated with more advanced stage at diagnosis.
Monitoring dietary supplement use is an important aspect of nutrition assessment, especially in populations with chronic health conditions or medical diagnoses. Demographic and personal characteristics, time passed since diagnosis, and stage of cancer at diagnosis are predictive of dietary supplement use by women at risk for breast cancer recurrence. Associations in this population may be present in other groups that are the object of nutrition intervention efforts.
开发一种收集、整理和分析乳腺癌复发风险女性营养及非营养膳食补充剂使用信息的方法，作为营养评估和监测的一部分，并描述在一项预防乳腺癌复发的临床试验入组时该人群膳食补充剂使用的相关特征。
横断面描述性研究设计。
在过去4年内被诊断为乳腺癌的女性（n = 435）。
根据主要营养成分和非营养成分对四次24小时饮食回顾中报告的膳食补充剂进行分类。描述膳食补充剂使用的患病率。使用卡方分析和逻辑回归研究补充剂使用与人口统计学及参与者特征之间的关联。
80.9%的女性报告使用膳食补充剂。补充剂使用可能性增加与人口统计学特征（如年龄较大、教育程度较高、白人种族与其他种族群体相比）和个人特征（如较低的体重指数、适度饮酒）相关。维生素C及相关化合物、其他营养素（如n-3脂肪酸、月见草油）和草药产品的使用与诊断后的月数呈负相关；其他补充剂（如鲨鱼软骨）的使用与诊断时更晚期别呈正相关。
监测膳食补充剂的使用是营养评估的一个重要方面，尤其是在患有慢性健康状况或有医学诊断的人群中。人口统计学和个人特征、诊断后经过的时间以及诊断时的癌症分期可预测乳腺癌复发风险女性的膳食补充剂使用情况。该人群中的关联可能存在于其他营养干预对象群体中。
