Klein R G, Campbell R J, Hunder G G, Carney J A
Mayo Clin Proc. 1976 Aug;51(8):504-10.
Although isolated foci of arteritis ("skip lesions") are presumed to occur in temporal arteritis, there is little documentation of their existence or significance. We have identified skip lesions in 17 of 60 patients (28%) with temporal arteritis, based on a retrospective and prospective examination of temporal artery biopsy specimens. By examining more than 6,000 serial sections of arteries from patients with skip lesions, we have found foci or arteritis as short as 330 mu in length in an otherwise normal biopsy specimen. Our study emphasizes the need to biopsy long segments of artery, to examine multiple histologic sections, and to perform a contralateral temporal artery biopsy when frozen-section examination of the first side is normal.
虽然颞动脉炎中推测会出现孤立的动脉炎病灶（“跳跃性病变”），但其存在或意义的文献记载很少。基于对颞动脉活检标本的回顾性和前瞻性检查，我们在60例颞动脉炎患者中的17例（28%）中发现了跳跃性病变。通过检查患有跳跃性病变患者的6000多个动脉连续切片，我们在其他方面正常的活检标本中发现了长度短至330微米的动脉炎病灶。我们的研究强调需要对较长的动脉段进行活检，检查多个组织学切片，并且当一侧的冰冻切片检查正常时，对侧颞动脉进行活检。
