Prabhakaran P S, Misra S, Kannan V, Chandrashekar M, Vijayakumar M, Veerendrakumar K V, Anantha N
Department of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, India.
Australas Radiol. 1998 Feb;42(1):42-6. doi: 10.1111/j.1440-1673.1998.tb00563.x.
A retrospective analysis of 14 cases of sacral chordoma seen between 1984 and 1993 at the Kidwai Memorial Institute of Oncology is reported. The mean patient age was 54 years, with 13 males and one female. Seventy-one per cent of patients presented with symptoms related to a painful sacral mass. Eight patients underwent radical surgery and two had adjuvant radiotherapy. One patient had a partial tumour resection. Three patients received radical radiotherapy. Two patients were offered only pain relief medication. The median follow-up was 33 months. The actuarial overall survival (OS) at 5 years was 48%. In the 12 patients in whom curative therapy was attempted, the 5-year OS was 56% and progression-free survival was 36%. Four patients developed local recurrence and three developed distant metastasis.
本文报告了对1984年至1993年间在基德瓦伊肿瘤纪念研究所所见的14例骶骨脊索瘤病例的回顾性分析。患者平均年龄为54岁，其中男性13例，女性1例。71%的患者表现出与骶骨肿物疼痛相关的症状。8例患者接受了根治性手术，2例接受了辅助放疗。1例患者进行了肿瘤部分切除术。3例患者接受了根治性放疗。2例患者仅接受了止痛药物治疗。中位随访时间为33个月。5年时的精算总生存率（OS）为48%。在尝试进行根治性治疗的12例患者中，5年OS为56%，无进展生存率为36%。4例患者出现局部复发，3例出现远处转移。
