Roseocardin, a novel cardiotonic cyclodepsipeptide from Trichothecium roseum TT103.
作者信息
Tsunoo A, Kamijo M, Taketomo N, Sato Y, Ajisaka K
机构信息
Meiji Institute of Health Science, Meiji Milk Products Co., Ltd., Kanagawa, Japan.
出版信息
J Antibiot (Tokyo). 1997 Dec;50(12):1007-13. doi: 10.7164/antibiotics.50.1007.
PMID:9510906
Abstract
A new cyclodepsipeptide, designated roseocardin, was isolated from the culture broth of Trichothecium roseum TT103. Roseotoxin B and destruxins A and B were also isolated during the same procedure. The structure of roseocardin was determined by EI-MS, NMR and X-ray crystallographic analysis. Roseocardin as well as the other cyclodepsipeptides were shown to produce positive inotropic effects on rat heart muscles.
摘要
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