Igarashi M, Nakamura H, Naganawa H, Takeuchi T
Institute of Microbial Chemistry, Tokyo, Japan.
J Antibiot (Tokyo). 1997 Dec;50(12):1026-31. doi: 10.7164/antibiotics.50.1026.
A novel herbicidal antibiotic, resormycin, was isolated from the culture broth of Streptomyces platensis MJ953-SF5. The structure of resormycin is determined to be (2Z)-2-N-[2N-[(3S)-3,6-diaminoheptanoyl]-(2S)-3-hydroxyva lyl]amino-3- (4-chloro-3,5-dihydroxy)phenylpropenoic acid by spectroscopic analyses, degradation studies and X-ray crystallography.
一种新型除草抗生素——间苯二酚霉素,是从普拉特链霉菌MJ953 - SF5的培养液中分离得到的。通过光谱分析、降解研究和X射线晶体学确定间苯二酚霉素的结构为(2Z)-2-N-[2N-[(3S)-3,6-二氨基庚酰基]-(2S)-3-羟基缬氨酰基]氨基-3-(4-氯-3,5-二羟基)苯丙酸。