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奎奴普丁/达福普汀对杰氏棒状杆菌和单核细胞增生李斯特菌临床分离株的最低抑菌浓度和最低杀菌浓度

Minimal inhibitory concentrations and minimal bactericidal concentrations of quinupristin/dalfopristin against clinical isolates of Corynebacterium jeikeium and Listeria monocytogenes.

作者信息

Moore L S, Schneider B, Holloway W J

机构信息

Medical Center of Delaware, Infectious Disease Research Laboratory, Wilmington 19899, USA.

出版信息

J Antimicrob Chemother. 1997 May;39 Suppl A:67-8. doi: 10.1093/jac/39.suppl_1.67.

DOI:10.1093/jac/39.suppl_1.67
PMID:9511066
Abstract

Thirty clinical isolates of Listeria monocytogenes and 30 clinical isolates of Corynebacterium jeikeium were tested against quinupristin/dalfopristin by the NCCLS broth macrodilution technique for determination of MICs. MBC testing was also performed on the 60 isolates. Quinupristin/dalfopristin MIC90 values against L. monocytogenes and C. jeikeium were 1.6 mg/L and 0.2 mg/L, respectively. Quinupristin/dalfopristin was bacteriostatic against these organisms.

摘要

采用美国国家临床实验室标准化委员会（NCCLS）肉汤稀释法，对30株单核细胞增生李斯特菌临床分离株和30株杰氏棒状杆菌临床分离株进行了奎奴普丁/达福普汀药敏试验，以测定最低抑菌浓度（MIC）。同时对这60株分离株进行了最低杀菌浓度（MBC）检测。奎奴普丁/达福普汀对单核细胞增生李斯特菌和杰氏棒状杆菌的MIC90值分别为1.6mg/L和0.2mg/L。奎奴普丁/达福普汀对这些菌具有抑菌作用。

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