Cochran D L, Schenk R K, Lussi A, Higginbottom F L, Buser D
Department of Periodontics, University of Texas Health Science Center at San Antonio 78284-7894, USA.
J Biomed Mater Res. 1998 Apr;40(1):1-11. doi: 10.1002/(sici)1097-4636(199804)40:1<1::aid-jbm1>3.0.co;2-q.
Many dental clinical implant studies have focused on the success of endosseous implants with a variety of surface characteristics. Most of the surface alterations have been aimed at achieving greater bone-to-implant contact as determined histometrically at the light microscopic level. A previous investigation in non-oral bone under short-term healing periods (3 and 6 weeks) indicated that a sandblasted and acid-etched titanium (SLA) implant had a greater bone-to-implant contact than did a comparably-shaped implant with a titanium plasma-sprayed (TPS) surface. In this canine mandible study, nonsubmerged implants with a SLA surface were compared to TPS-coated implants under loaded and nonloaded conditions for up to 15 months. Six foxhound dogs had 69 implants placed in an alternating pattern with six implants placed bilaterally in each dog. Gold crowns that mimicked the natural occlusion were fabricated for four dogs. Histometric analysis of bone contact with the implants was made for two dogs after 3 months of healing (unloaded group), 6 months of healing (3 months loaded), and after 15 months of healing (12 months loaded). The SLA implants had a significantly higher (p < 0.001) percentage of bone-to-implant contact than did the TPS implants after 3 months of healing (72.33 +/- 7.16 versus 52.15 +/- 9.19; mean +/- SD). After 3 months of loading (6 months of healing) no significant difference was found between the SLA and TPS surfaced implants (68.21 +/- 10.44 and 78.18 +/- 6.81, respectively). After 12 months of loading (15 months of healing) the SLA implants had a significantly greater percentage (p < 0.001) of bone-to-implant contact than did the TPS implants (71.68 +/- 6.64 and 58.88 +/- 4.62, respectively). No qualitative differences in bone tissue were observed between the two groups of implants nor was there any difference between the implants at the clinical level. These results are consistent with earlier studies on SLA implants and suggest that this surface promotes greater osseous contact at earlier time points compared to TPS-coated implants.
许多牙科临床种植体研究都聚焦于具有各种表面特征的骨内种植体的成功率。大多数表面改变旨在通过光镜下的组织计量学方法实现更大的骨与种植体接触。先前在短期愈合期（3周和6周）对非口腔骨进行的一项研究表明，喷砂和酸蚀钛（SLA）种植体比具有钛等离子喷涂（TPS）表面的形状相当的种植体具有更大的骨与种植体接触。在这项犬下颌骨研究中，将具有SLA表面的非潜入式种植体与TPS涂层种植体在加载和未加载条件下进行了长达15个月的比较。六只猎狐犬，每只犬双侧交替植入69颗种植体，共植入6颗。为四只犬制作了模拟自然咬合的金冠。在愈合3个月（未加载组）、6个月（加载3个月）和15个月（加载12个月）后，对两只犬的种植体骨接触进行了组织计量学分析。愈合3个月后，SLA种植体的骨与种植体接触百分比显著高于TPS种植体（p < 0.001）（分别为72.33 +/- 7.16和52.15 +/- 9.19；平均值 +/- 标准差）。加载3个月（愈合6个月）后，SLA和TPS表面种植体之间未发现显著差异（分别为68.21 +/- 10.44和78.18 +/- 6.81）。加载12个月（愈合15个月）后，SLA种植体的骨与种植体接触百分比显著高于TPS种植体（p < 0.001）（分别为71.68 +/- 6.64和58.88 +/- 4.62）。两组种植体之间未观察到骨组织的定性差异，临床水平上种植体之间也没有差异。这些结果与早期关于SLA种植体的研究一致，表明与TPS涂层种植体相比，该表面在更早的时间点促进了更大的骨接触。
