Aĭlamazian E K
Vestn Ross Akad Med Nauk. 1998(1):6-11.
Introduction of cordocentesis into clinical practice has made progress in antenatal diagnosis and treatment of congenital (hereditary and acquired) fetal diseases. Cytogenetic, molecular biological, biochemical, and immunological studies of fetal blood have substantial advantages for prenatal diagnosis. Direct administration of blood components and drugs into fetal blood circulation is the treatment of choice in some fetal diseases, severe types of hemolytic disease. Intravascular injection of myorelaxants was shown to greatly favour long-term intrauterine interventions. The potentialities, advances, and prospects of intrauterine surgical correction of fetal developmental disorders are discussed.
将脐带穿刺术引入临床实践,在先天性(遗传性和后天性)胎儿疾病的产前诊断和治疗方面取得了进展。对胎儿血液进行细胞遗传学、分子生物学、生化和免疫学研究,在产前诊断方面具有显著优势。将血液成分和药物直接注入胎儿血液循环是某些胎儿疾病(严重类型的溶血病)的首选治疗方法。血管内注射肌松剂被证明极大地有利于长期的宫内干预。本文讨论了宫内手术矫正胎儿发育障碍的潜力、进展和前景。