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Effects of prenatal alcohol consumption on open-field behaviour and alcohol preference in rats.

作者信息

Bond N W, Di Giusto E L

出版信息

Psychopharmacologia. 1976 Mar 16;46(2):163-5. doi: 10.1007/BF00421386.

DOI:10.1007/BF00421386
PMID:951453
Abstract

Throughout gestation pregnant Wistar rats consumed a liquid diet containing sustagen and ethanol. Control mothers were fed on lab chow. Subsequently, the offspring of the ethanol-fed mothers displayed significantly greater activity (ambulation and rearing) in an open-field test. Further, pups whose mothers were exposed to ethanol consumed significantly more ethanol in a preference test, compared to control offspring.

摘要

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Effects of prenatal alcohol consumption on open-field behaviour and alcohol preference in rats.
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本文引用的文献

1
A family study of the hyperactive child syndrome.多动症儿童综合征的家族研究。
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2
Prenatal psychological stress and offspring behavior in rats and mice.大鼠和小鼠的产前心理应激与后代行为
Dev Psychobiol. 1971;4(3):193-248. doi: 10.1002/dev.420040302.
产前乙醇暴露会错误调节参与铁稳态的基因,促进铁依赖性海马突触传递和可塑性的适应不良。
Front Pharmacol. 2019 Nov 7;10:1312. doi: 10.3389/fphar.2019.01312. eCollection 2019.
4
Brain DNA damage and behavioral changes after repeated intermittent acute ethanol withdrawal by young rats.幼鼠反复间歇性急性乙醇戒断后的脑DNA损伤及行为变化
Psychopharmacology (Berl). 2015 Oct;232(19):3623-36. doi: 10.1007/s00213-015-4015-x. Epub 2015 Aug 2.
5
Prenatal alcohol exposure alters methyl metabolism and programs serotonin transporter and glucocorticoid receptor expression in brain.孕期酒精暴露会改变甲基代谢,并影响大脑中血清素转运体和糖皮质激素受体的表达。
Am J Physiol Regul Integr Comp Physiol. 2015 Sep;309(5):R613-22. doi: 10.1152/ajpregu.00075.2015. Epub 2015 Jul 15.
6
Effects of prenatal alcohol and cigarette exposure on offspring substance use in multiplex, alcohol-dependent families.产前酒精和香烟暴露对多重酒精依赖家庭中后代物质使用的影响。
Alcohol Clin Exp Res. 2014 Dec;38(12):2952-61. doi: 10.1111/acer.12569.
7
Genetic and environmental influences on ethanol consumption: perspectives from preclinical research.遗传和环境因素对乙醇消费的影响:来自临床前研究的观点。
Alcohol Clin Exp Res. 2010 Jun;34(6):976-87. doi: 10.1111/j.1530-0277.2010.01172.x. Epub 2010 Apr 5.
8
Ontogeny of the enhanced fetal-ethanol-induced behavioral and neurophysiologic olfactory response to ethanol odor.乙醇诱导的行为和神经生理嗅觉反应增强的胎儿期发生过程。
Alcohol Clin Exp Res. 2010 Feb;34(2):206-13. doi: 10.1111/j.1530-0277.2009.01083.x. Epub 2009 Nov 24.
9
Binge ethanol exposure in late gestation induces ethanol aversion in the dam but enhances ethanol intake in the offspring and affects their postnatal learning about ethanol.妊娠后期大量接触乙醇会使母鼠产生乙醇厌恶,但会增加后代的乙醇摄入量,并影响它们出生后对乙醇的学习。
Alcohol. 2009 Sep;43(6):453-63. doi: 10.1016/j.alcohol.2009.08.001.
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Prenatal alcohol exposure: fetal programming and later life vulnerability to stress, depression and anxiety disorders.产前酒精暴露:胎儿编程与后期生活中应激、抑郁和焦虑障碍易感性。
Neurosci Biobehav Rev. 2010 May;34(6):791-807. doi: 10.1016/j.neubiorev.2009.06.004. Epub 2009 Jun 21.